Publications

Arbab M*, Matuszek Z*, Kray KM, Du A, Newby GA, Blatnik AJ, Raguram A, Richter MF, Zhao KT, Levy JM, Shen MW, Arnold WD, Wang D, Xie J, Gao G, Burghes AHM, Liu DR. Base editing rescue of spinal muscular atrophy in cells and in mice. Science (2023) Mar 30; online ahead of print

Neugebauer ME, Hsu A, Arbab M, Krasnow NA, McElroy AN, Pandey S, Doman JL, Huang TP, Raguram A, Banskota S, Newby GA, Tolar J, Osborn MJ, Liu DR. Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity. Nature Biotechnology (2022) Nov 10; online ahead of print.

Koblan LW*, Arbab M*, Shen MW*, Hussmann JA, Anzalone AV, Doman JL, Newby GA, Yang D, Mok B, Reploge JM, Xu A, Sisley TA, Weissman JS, Adamson B, Liu DR. Development of C•G-to- G•C transversion base editors from CRISPRi screens, target-library analysis and machine learning. Nature Biotechnology (2021) Nov;39(11):1414-1425.

Arbab M*, Shen MW*, Mok B, Wilson C, Matuszek Z, Cassa CA, Liu DR. Determinants of Base Editing Outcomes from Target Library Analysis and Machine Learning. Cell (2020) Jul 23;182(2):463-480.e30.

Miller SM*, Wang T*, Randolph PB, Arbab M, Shen MW, Huang TP, Matuszek Z, Newby GA, Rees HA, Liu DR. Continuous evolution of SpCas9 variants compatible with non-G PAMs. Nature Biotechnology (2020) Apr;38(4):471-481.

Shen MW*, Arbab M*, Hsu JY, Worstell D, Culbertson SJ, Krabbe O, Cassa CA, Liu DR, Gifford DK, Sherwood RI, Predictable and precise template-free CRISPR editing of pathogenic variants. Nature (2018) 563, 646–651.

Arbab M., Sherwood RI, Self-Cloning CRISPR. Current Protocols in Stem Cell Biology (2016) 38:5B.5.1-5B.5.16.

Arbab M., Srinivasan S, Hashimoto T, Geijsen N, Sherwood RI. Cloning-free CRISPR. Stem Cell Reports (2015) 5, 1-10.

Welling M, Chen H, Muñoz J, Musheev MU, Kester L, Junker JP, Mischerikow N, Arbab M, Kuijk E, Silberstein L, Kharchenko PV, Geens M, Niehrs C, van de Velde H, van Oudenaarden A, Heck AJR, Geijsen N. DAZL regulates Tet1 translation in murine embryonic stem cells. EMBO Reports (2015) 16, 791-802.

Arbab M, Baars S, Geijsen N. Modeling motor neuron disease: the matter of time. Trends in Neurosciences (2014) 37, 642-52.

Arbab M, Mahony S, Cho H, Chick JM, Rolfe PA, van Hoff JP, Morris VWS, Gygi SP, Maas RL, Gifford DK, Sherwood RI. A multi-parametric flow cytometric assay to analyze DNA-protein interactions. Nucleic Acids Research (2013) 41, e38.